Ngwa nyocha ngwa ngwa nke COVID-19 na-anọpụ iche (Colloidal Gold)

Ihe nlere ngwa ngwa nke COVID-19 na-anọpụ iche nke mmadụ (Colloidal Gold) egosipụtara

Nkọwa dị mkpirikpi:

Nkọwa ngwaahịa

Ebumnuche iji:

◆N'ihi na nchọpụta nke neutralizing mgbochi.

◆COVID-19 Neutralizing Antibody Rapid Test Kit (Colloidal Gold) bụ ihe mgbochi na-asọpụta immunoassay na-ezube ịchọpụta qualitative nke na-ewepụ mgbochi SARS-CoV-2 n'ọbara mmadụ dum, serum ma ọ bụ plasma dị ka ihe enyemaka na ọkwa nyocha nke mgbochi mmadụ. - akwụkwọ akụkọ coronavirus neutralizing antibody titer.

Usoro nlele

◆Ọbara dum, Serum, Plasma

Ụkpụrụ ọrụ:

◆Ngwa a na-eji immunochromatography.Kaadị ule ahụ nwere:1)colloidal gold-labeled recombinant novel coronavirus S-RBD antigen na mma akara mgbochi ọla edo;2) otu ahịrị nchọpụta (T line) na otu akara njikwa mma (C ahịrị) nke akpụkpọ ahụ nitrocellulose.Eji protein mmadụ ACE2 mechiri ahịrị T ahụ maka ịchọpụta coronavirus na-ewepụ mgbochi mgbochi yana eriri C na-enweghị ike imegharị ya na mgbochi njikwa mma.

◆Mgbe agbakwunyere ego kwesịrị ekwesị nke nlele ule na oghere nlele nke kaadị ule ahụ, ihe nlele ahụ ga-aga n'ihu na kaadị ule n'okpuru ọrụ nke capillary.Ọ bụrụ na ihe nlele ahụ nwere akwụkwọ akụkọ coronavirus na-egbochi mgbochi, mgbochi ahụ ga-ejikọta ya na coronavirus antigen nke akpọrọ colloidal ọla edo.A ga-ejide akwụkwọ akụkọ coronavirus nke ọzọ edobere ọla edo dị na ogige ahụ site na protein ACE2 nke mmadụ anaghị emegharị ahụ.

akpụkpọ ahụ na-etolite ahịrị T na-acha odo odo-acha ọbara ọbara, ike nke t akara n'ụzọ dabara adaba na ntinye nke mgbochi.

◆Kaadị ule ahụ nwekwara akara njikwa mma C. Akara njikwa mma fuchsia C kwesịrị ịpụta n'agbanyeghị ma akara ule na-egosi.Ọ bụrụ na ahịrị njikwa mma C egosighi, nsonaazụ nnwale ahụ abaghị uru, yana ekwesịrị iji kaadị ule ọzọ nwalee ihe nlele ọzọ.

Nkọwa ngwaahịa:

◆ Nnukwu nnukwu akụkụ okuku ume na ọrịa coronavirus 2 (SARS-CoV-2, ma ọ bụ 2019-nCoV) bụ nje RNA ezi uche na-abụghị akụkụ nke kpuchiri ya.Ọ bụ ya

Ihe kpatara COVID-19, nke na-efe efe n'ime mmadụ.

◆SARS-CoV-2 nwere ọtụtụ protein nhazi gụnyere spike (S), envelopu (E), akpụkpọ ahụ (M) na nucleocapsid (N).Protein spike (S) nwere ngalaba nnabata nnabata (RBD), nke na-ahụ maka ịmata onye na-anabata sel, antigens na-agbanwe enzyme-2 (ACE2).A na-achọta ya onye na-anabata ACE2 na-eduga na endocytosis n'ime sel ndị ọbịa nke ngụgụ miri emi na mmegharị nje.

◆ Ọrịa na SARS-CoV-2 ma ọ bụ SARS-COV-2 ịgba ọgwụ mgbochi ọrịa na-amalite nzaghachi mgbochi iji mepụta ọgwụ nje na-enye nchebe pụọ na ọrịa nje n'ọdịnihu.Ihe mgbochi mgbochi mmadụ na-elekwasị anya na ngalaba nnabata ACE2 (RBD) nke protein spike SAR-COV-2 na-egosi nkwa ọgwụgwọ yana arụmọrụ na nchekwa.

◆ Serum ma ọ bụ plasma specimen/ọbara mkpịsị aka.

◆N'ihi na ọkara-quantitative nchọpụta nke neutralizing mgbochi.

◆Nnwale mgbochi mgbochi mmadụ nwere ike ịchọpụta ma enwere ọgwụ mgbochi mgbochi megide SARS-CoV-2 n'ime ahụ.

◆Nyere aka soro ogologo ndụ mgbochi nchebe mgbe ịgba ọgwụ mgbochi ahụ gasịrị.